Digital biomarkers for life science research

The brain and body, measured in the real world.

Using AI to decode neurophysiology and make brain medicine measurable.

Neurophysiology, measured at home

Multiple signals, one decoded timeline.

Neurophysiology is stuck in the lab. We build the wearables that read it at home, and the AI layer that decodes it, starting with sleep.

Sleep

Sleep organisation, stability, intensity, and how it is regulated across nights.

Cortical function

Cortical slowing, excitability, and signal complexity, the markers that track cognitive status.

Autonomic regulation

Cardiac autonomic tone and arousal response, resolved by sleep stage.

Motor & movement

Muscle activation and movement kinematics, linking neural command to mechanical output.

Research hub Coming soon

Nexus headband

Sleep-EEG headband, worn overnight at home. Hours of uninterrupted brain signal, night after night.

Paragit sleeve

Flexible EMG sleeve for the arm and leg. Muscle activity and movement, day and night.

Sleep is a Window into Brain Health

The Nexus platform

Sleep analysis that shows its work.

A night in a lab tells you about one night. Nexus analyzes every night your participants sleep at home, and every number it returns comes with the method behind it.

AnalyzeA full night in detail Every 30 seconds of the night is staged, so you see the cycles and how often sleep broke up. Each stage carries a confidence score, and the raw signal is one click away.

TrackMany nights for context One bad night tells you nothing. Each participant is read against their own baseline across the study, so a real change stands out from a restless one.

DefendAnalytics you can trust Every result shows the method behind it and how clean the signal was. We match published methods to 1e-3, so a reviewer can rerun the analysis and get the same answer.

nexus.insai.tech/analysis

One night in the Nexus portal: hypnogram, staging confidence, sleep cycles, efficiency and stage composition

Nexus trends, markers across 14 nights against each participant's own baseline, with low-signal nights excluded

Nexus signal quality: Data-Trust score, per-channel quality worst first, coverage and confidence, with detected sleep oscillations below

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Get started

Start on your data. Scale with at-home studies.

Upload and analyze nights you already have. Run your next study on the same platform, and we ship devices straight to your participants.

Beta

For researchers with recordings in hand

Software · Nexus portal

Upload your nights. Get them analyzed.

Every number comes back with its method and its signal quality, so you can defend what you report.

Upload and manage EDFs
Staging with U-Sleep, YASA, CBraMod, Hypnos, and others
Architecture, regularity, spindles, slow waves, and spectral markers
A signal-quality score on every night, with the raw trace behind it
CLI and API that drop into your own workflows

Request access

For teams designing a new study

At-home studies

Every bedroom becomes a study site.

You design the study. We handle the hardware and the participants, and every night comes back analyzed.

Nexus headband per participant, Paragit sleeve on request
We fit participants and handle their support
Compliance monitored, dropouts flagged early
Nights sync automatically and come back staged
The same markers and provenance as the portal

Book a protocol call

Applications

Measured from home, at scale.

Accessible sleep studies for the protocols where sleep actually matters.

Longevity

Older woman asleep in her own bed wearing the Nexus headband

Health and longevity

Slow-wave sleep and sleep regularity move slowly and swing night to night. A run of nights at each timepoint reads a participant against their own average.

Nexus headbandSlow-wave sleepSleep regularity

Neurology

Older man at home wearing the forearm sensor sleeve

Parkinson's, between visits

MDS-UPDRS comes months apart, scored by hand. We read the brain on the nights in between, with EMG and motion from the sleeve.

Headband + sleeveSpectral slowingEMG + motion

Psychiatry At-home sleep study with the Nexus headband

Psychiatry and mental health

Mood and cognition trials run on wrist actigraphy, which infers sleep from movement. The headband reads EEG, so you follow REM and slow-wave sleep through an episode.

Nexus headbandSleep stagingREM + slow-wave

For therapy developers: a secondary endpoint beside your primary measure, where rating scales aren't sharp enough.

Collaborators